1. What is the FRAX Score?

The FRAX® tool is a computer-based algorithm that calculates the 10-year probability of a major osteoporotic fracture (hip, spine, humerus or wrist fracture) and the 10-year probability of hip fracture.

2. How Does the Calculator Work?

The calculator uses the FRAX algorithm:

Where:

• Age — Age in years
• BMI — Body Mass Index in kg/m²

Explanation: The FRAX algorithm integrates clinical risk factors with bone mineral density (BMD) to estimate fracture probability.

3. Importance of FRAX Calculation

Details: FRAX score helps clinicians identify patients at high risk of osteoporotic fractures who may benefit from pharmacological treatment.

4. Using the Calculator

Tips: Enter age in years, BMI in kg/m², and other relevant clinical risk factors. All values must be valid.

5. Frequently Asked Questions (FAQ)

Q1: What is a clinically significant FRAX score?
A: Treatment is typically recommended when the 10-year probability of major osteoporotic fracture is ≥20% or hip fracture probability is ≥3%.

Q2: Can FRAX be used without BMD measurement?
A: Yes, FRAX can be calculated with or without BMD, though accuracy improves with BMD input.

Q3: What are the limitations of FRAX?
A: FRAX may underestimate risk in certain populations and doesn't account for all risk factors like falls risk or dose of glucocorticoids.

Q4: How often should FRAX be recalculated?
A: FRAX should be reassessed every 2-5 years or when clinical risk factors change significantly.

Q5: Is FRAX validated for all populations?
A: FRAX models are country-specific and should be used with the appropriate country model for accurate assessment.