P/F Ratio Formula:
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The P/F ratio (PaO2/FiO2 ratio) is a clinical indicator used to assess the severity of hypoxemia and respiratory failure. It's commonly used in critical care settings to evaluate patients with acute respiratory distress syndrome (ARDS) and other lung conditions.
The calculator uses the P/F ratio formula:
Where:
Explanation: The ratio compares the oxygen level in arterial blood to the concentration of oxygen being inhaled, providing a standardized measure of oxygenation efficiency.
Details: The P/F ratio is crucial for diagnosing and classifying the severity of ARDS, guiding treatment decisions, and monitoring patient response to respiratory therapies and ventilator management.
Tips: Enter PaO2 in mmHg and FiO2 as a decimal (e.g., 0.21 for room air, 0.4 for 40% oxygen). Both values must be valid (PaO2 > 0, FiO2 between 0.21-1.0).
Q1: What is a normal P/F ratio?
A: A normal P/F ratio is typically >400 mmHg. Values between 300-400 indicate mild hypoxemia, 200-300 moderate, and <200 severe hypoxemia.
Q2: How is the P/F ratio used in ARDS diagnosis?
A: ARDS is diagnosed when P/F ratio is ≤300 mmHg with PEEP ≥5 cm H2O, with bilateral opacities on chest imaging not fully explained by cardiac failure.
Q3: When should arterial blood gas be measured?
A: ABG should be measured when there's concern about oxygenation, ventilation, or acid-base status, particularly in critically ill patients or those with respiratory distress.
Q4: Are there limitations to the P/F ratio?
A: The ratio doesn't account for PEEP levels, patient effort, or cardiac output. It should be interpreted in the full clinical context.
Q5: How does altitude affect the P/F ratio?
A: At higher altitudes, normal PaO2 values are lower, which affects the P/F ratio. Reference values should be adjusted for altitude.